| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_384fe636cd448f00f2cd7b1d374569b8 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-5156
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-5158
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-03
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-7051 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-867
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0011 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-867
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-17 |
| filingDate |
2019-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_182b3f47b5b45d61dec37f49bee7efbf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_501df43d20c356763d0c98c5126844ac |
| publicationDate |
2020-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2020119048-A1 |
| titleOfInvention |
Immune cell containing tumor antigen recognition receptor and application thereof |
| abstract |
An immune cell containing a tumor antigen recognition receptor and an application thereof. The immune cell containing the tumor antigen recognition receptor expresses hyaluronidase, and the hyaluronidase is: a) a full-length protein anchored to the immune cell; or b) a soluble protein secreted to the outside of the immune cell. An application of the immune cell in preparation of drugs for treating tumors. By means of the described immune cell containing the tumor antigen recognition receptor, the extracellular matrix structure of a microenvironment may be changed to normalize a tumor immune microenvironment, so that the immune cell may effectively approach and kill tumor cells. With the help of the soluble PH20 protein, the immune cell containing the tumor antigen recognition receptor may also improve a tumor microenvironment and effectively kill tumor cells. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023168305-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-116426483-A |
| priorityDate |
2017-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |