| abstract |
The invention is directed to methods of treatment of colorectal cancer, said treatment comprising the administration of the anti-alpha-v integrin (receptor) antibody Abituzumab. Preferably, the invention relates to methods of treating colorectal cancer, Stage II-IV colorectal cancer, metastatic colorectal cancer, left-sided colorectal cancer and/or left-sided metastatic colorectal comprising the administration of said Abituzumab to patients in need thereof. The instant invention also relates the use of Abituzumab for the manufacture of a medicament for treating colorectal cancer, preferably colorectal cancer as defined herein, and/or use of Abituzumab for the manufacture of a medicament for treating colorectal cancer in combination with suitable targeted therapy concepts, such as growth factor or growth factor receptor targeting monoclonal antibodies, and/or chemotherapy. |