http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020071501-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_268be9afa00cf55b5aa72b1612151ecb |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6869 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-06 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6869 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-48 |
filingDate | 2019-10-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b57c42b204d0e1a29d044deb719d0d48 |
publicationDate | 2020-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2020071501-A1 |
titleOfInvention | Cell-information processing method |
abstract | The purpose of the present invention is to provide a cell-information processing method for efficiently analyzing mechanisms of action of changes in individual cell populations in the presence of a mixture of different multiple types of cell populations. A cell-information processing method according to the present invention includes: a cell retrieving step for preparing at least two prescribed vessels in which target cell groups containing different multiple types of cells are seeded, subjecting the target cells to a prescribed cell stimulation to culture said cells, and retrieving all of the cells, one vessel at a time, at two or more points in time; a single-cell preparing step for preparing single cells from all of the cells retrieved at each point in time; a single-cell-data acquiring step for acquiring single-cell data from the individual cells prepared as single cells at each point in time; a grouping step for grouping, on the basis of the single-cell data at each point in time, all of the cells retrieved at each point in time into multiple cell populations having a common first cell characteristic to plot said cell populations on a two-dimensional plane or in a three-dimensional space, performing processing for identifying, on the basis of a second cell characteristic, cell types of the grouped individual cell populations, and acquiring a clustering result at each point in time; a cell-change detecting step for comparing the clustering results at the individual points in time, thereby detecting changes over time in the cell populations of the same cell types; and a mechanism-of-action analyzing step for analyzing, on the basis of the detection results, mechanisms of action of the changes over time in the cell populations of the same cell types. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110264501-A |
priorityDate | 2018-10-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 242.