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filingDate 2016-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2018-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2018514195-A
titleOfInvention Integrated cellular functionality and molecular profiling
abstract Described herein is a method for assessing cell activity comprising placing a cell population on a region; assaying the dynamic behavior of the cell population as a function of time; Identifying the cells of interest based on specific behavior; characterizing the molecular profile of the cells; and correlating the obtained information. The dynamic behaviors that are assayed include cell activation, cell inhibition, cell interaction, protein expression, protein secretion, cell proliferation, cell shape change, motility, cell death, cell cytotoxicity, There may be mentioned cell lysis and combinations thereof. Sensors that work with regions can be utilized to facilitate the assay. The molecular profile of a cell can be characterized by various methods such as DNA analysis, RNA analysis, and protein analysis. Dynamic behavior and molecular profiles can be used for various purposes such as predicting the clinical outcome of treatment, screening cells, facilitating treatment, diagnosing disease, and monitoring cellular activity. Can be correlated. [Selection] Figure 1
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