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filingDate 2019-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8269e88563554cb5b1bf019d051a401
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publicationDate 2019-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2019216667-A1
titleOfInvention Method for generating induced neural stem cells directly reprogrammed from non-neural cells by using sox2 and c-myc
abstract The present invention relates to a method for generating neural stem cells induced from non-neural cells through direct reprogramming and a use thereof. Because the method for generating induced neural stem cells according to the present invention allows the generation of induced neural stem cells from non-neural cells even when only the two inducing factors Sox2 and c-Myc are used, the method can generate induced neural stem cells more effectively than conventional generation methods using four or five inducing factors. The induced neural stem cells generated by the method exhibit excellent differentiation potency and proliferation activity and thus can be applied to therapeutic purposes in future.
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