Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d69445b2bef2798628ddc9a3f83d0174 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y101-01201 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0006 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P33-06 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63 |
filingDate |
2019-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c454f11d5d5c14a4d199adda3b1420bf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ff98113e9869e43678a6332bcb1da25 |
publicationDate |
2019-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2019209105-A2 |
titleOfInvention |
NAD+ DEPENDENT 7β-HYDROXYSTEROID DEHYDROGENASE |
abstract |
The present invention relates to a NAD+ dependent 7β- hydroxysteroid dehydrogenases and to methods of providing a 7β- hydroxysteroid dehydrogenase with a co-substrate specificity of NAD+ instead of NADP+. The invention further relates to methods for converting cholic acid (CA) and/or chenodeoxycholic acid (CDCA) into ursocholic acid (UCA) and/or ursodeoxycholic acid (UDCA) respectively, and more specifically methods for converting 7-oxo-deoxycholic acid (7-oxo-DCA) and/or 7-oxo-lithocholic acid (7-oxo LCA) into ursocholic acid (UCA) and/or ursodeoxycholic acid (UDCA) respectively, by using an NAD+ dependent 7β- hydroxysteroid dehydrogenase. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114250205-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113462665-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115806951-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115806951-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113025589-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113025589-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114250205-B |
priorityDate |
2018-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |