Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0e25cb804ee22e25b0137883ed4bae97 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1df8a46845cd47b585a302dfe4006e09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a680aa44861d78bf9bdd6eeca28f9d4a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e2ed1f1e5545115ad3ad71e9e32d4e61 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-713 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-3955 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-713 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
filingDate |
2019-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_57a3732fedb0108ee34247cc60df1743 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e64bf6dd847e4ed0ce43a5bdd4f53cc6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_852dca06c6e3108fd59b7e0b6c0dd2df http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f121a63811d0c0d99611dad081dff85 |
publicationDate |
2019-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2019150309-A1 |
titleOfInvention |
Modulators of gpr68 and uses thereof for treating and preventing diseases |
abstract |
This disclosure provides novel compositions, methods, and therapeutic uses related to modulators of a GPR68 gene product. Some embodiments disclosed herein provide methods of modulating flow-mediated dilation (FMD) response or flow-mediated outward remodeling (FMR) of small-diameter arteries, or reducing systemic vascular resistance (SVR) in a subject in need thereof comprising administering a modulator of a GPR68 gene product to the subject. Some embodiments disclosed herein provide methods of treating a cardiovascular disease in a subject in need thereof comprising administering a pharmaceutical composition comprising a modulator of a GPR68 gene product to the subject. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113373170-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023285878-A1 |
priorityDate |
2018-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |