http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019070162-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0e6a1441e6b4c2a00ac6e83b5a3ca016 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12R2001-19 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-205 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-70 |
| filingDate | 2018-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc4b6557853d223dff9342a7bb7993c1 |
| publicationDate | 2019-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2019070162-A1 |
| titleOfInvention | STOMM-PRODUCER SOMATOTROPINA Predominantly mono-dimensional form |
| abstract | The invention relates to molecular biology, biotechnology, medicine and can be used for the production of human growth hormone. A plasmid DNA for the synthesis of human growth hormone in Escherichia coli cells is proposed, represented by the vector pET-21a (+), the sequence from the T7 promoter by lac operator is modified and characterized by SEQ ID NO: 3 containing the insert of the gene encoding a protein characterized by the amino acid sequence SEQ ID NO: 1 optimized for codon composition for expression in Escherichia coli cells. Also proposed is a strain producing human growth hormone, based on Escherichia coli BL21 (DE3) cells transformed with the described plasmid DNA. The use of the proposed inventions allows to achieve a significant increase in the yield of the monomeric form of somatotropin, up to 80%. |
| priorityDate | 2017-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 372.