| abstract |
Methods for treatment of fibrotic diseases using compounds of formula I wherein R A is hydrogen, R 7 and R 8 are independently selected from H and SO 2 NR 3 R 4 , one of R 7 and R 8 is hydrogen, and R 1 , R 2 , R 3 , and R 4 are each independently selected from H, alkyl, heteroalkyl, cycloalkyl, arylcycloalkyl, aryl, heteroaryl, heterocycloalkyl, and each of NR 1 R 2 and NR 3 R 4 can independently combine to form a heterocycloalkyl, and wherein said alkyl, heteroalkyl, cycloalkyl, arylcycloalkyl, aryl, heteroaryl, or heterocycloalkyl may be optionally substituted, or a pharmaceutically acceptable salt, ester, amide, stereoisomer, geometric isomer or prodrug thereof. |