| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_42d3020ad67c717f34d32e1448c74281 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-10 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-00 |
| filingDate |
2018-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_31c0114579ad34012fc5038e971fe8a0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8821aba803c39ae529a5f3fce8dfda62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_00625e848b7e2f7934bc0ecca0ff6748 |
| publicationDate |
2018-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2018177825-A1 |
| titleOfInvention |
Orthogonal protecting groups for the preparation of stereodefined phosphorothioate oligonucleotides |
| abstract |
The present invention relates to the field of stereodefined phosphorothioate oligonucleotides and to stereodefining nucleoside monomers comprising an amine containing chiral auxiliary group, and methods of orthogonally protecting the nitrogen of chiral auxiliaries during oligonucleotide synthesis, preventing post elongation chain cleavage, increasing yield and purity of stereodefined phosphorothioate oligonucleotides. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11667660-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020191252-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020212301-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020104492-A1 |
| priorityDate |
2017-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |