| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_42d3020ad67c717f34d32e1448c74281 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-02 |
| filingDate |
2017-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2b3f1302acede52490de07bebcd0a727
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6f212c12ce8a99845b8dec1414a647f0 |
| publicationDate |
2017-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2017194498-A1 |
| titleOfInvention |
Enhanced coupling of stereodefined oxazaphospholidine phosphoramidite monomers to nucleoside or oligonucleotide |
| abstract |
The present invention relates to the field of stereodefined phosphorothioate oligonucleotides and to stereodefining nucleoside monomers and methods of synthesis of stereodefined oligonucleotides. Herein are disclosed solvent compositions which provide enhanced solubility and stability of stereodefining nucleoside monomers, and can be used to improve the coupling efficacy of such monomers in oligonucleotide synthesis. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10428019-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10160969-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019002237-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10149905-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020104492-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10280192-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10329318-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018177825-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11667660-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10590413-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11591362-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10307434-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9982257-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10144933-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10167309-B2 |
| priorityDate |
2016-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |