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filingDate 2017-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_11ee8d945315e9d723669f60be55a952
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publicationDate 2018-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2018101327-A1
titleOfInvention Method for estimating gleason score of prostate cancer, method for estimating pathological stage, and method for acquiring supplementary information, all on the basis of specific psa content in specimen
abstract The present invention provides methods that are for acquiring various types of supplementary information used for diagnosis or treatment of prostate cancer, and that can be implemented in a less-invasive manner at a low cost. Provided are, by measuring the contained amount of prostate specific antigen (PSA) having a β-N-acetylgalactosamine residue at a non-reducing terminal of a sugar chain in a specimen, and comparing the measurement with a threshold value: (1) a method for estimating whether a Gleason score (primary pattern and secondary pattern) is less than or not less than a prescribed value, (2) a method for estimating whether the pathological staging (pT) is less than or not less than a prescribed value, and (3) a method for acquiring assessment information indicating diagnosis or treatment should be actively conducted because a GS at full extraction is expected to be higher than a GS at biopsy.
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