http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017056844-A1

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filingDate 2016-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_abcfcaec21313710eabd48e0ede8276f
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publicationDate 2017-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2017056844-A1
titleOfInvention Method for estimating pathological tissue diagnosis result (gleason score) of prostate cancer
abstract The present invention provides a method for obtaining an index value that is used in a pathological tissue diagnosis of prostate cancer, which can be performed at low invasiveness and at low cost. The method according to the present invention is a method for estimating a Gleason score that represents the degree of malignancy of prostate cancer. In the method, the content of a prostate-specific antigen (PSA), which is an antigen having an N-acetylgalactosamine residue at a non-reductive terminal of a sugar chain, in a sample is determined, and it is estimated that the Gleason score is 7 or more when the measurement value is greater than a threshold value, or it is estimated that the Gleason score is 6 or less when the measurement value is smaller than the threshold value. It is preferred that the quantification of the PSA is carried out by a method involving a step of binding a molecule having affinity for a β-N-acetylgalactosamine residue, e.g., Wisteria floribunda agglutinin (WFA), soybean agglutinin (SBA) or Vicia villosa lectin (VVL), or an anti-β-N-acetylgalactosamine antibody to the PSA.
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priorityDate 2015-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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