| abstract |
Provided are an ATG analogue, a preparation method therefor and a use thereof, the specific structure of the ATG analogue is as shown in the following three general formulae: formula (I), formula (II), and formula (III) wherein X/Y/Z can be respectively selected from C, N, S and O, and R1, R2, R3, R4 and R5 are each respectively selected from: H, a CH3 group, an aliphatic or aromatic hydrocarbon group, a nitro group, a phosphate group, a sulphide group, a sulphone group, a nitrile group, a heterocyclic group, a borate or boric acid group, an ester group and an amine group. The ATG analogue provided by the present invention has better water solubility and has an effect of preventing being decomposed in primary metabolism. |