Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3696b0a5c800add4fbf4460737ed94a1 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-71 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57415 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B30-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-567 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 |
filingDate |
2017-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_edf2d7a0a709fa02fea6b74bbd974191 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a473e55553eb65f7a80b82a172497c2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c9fde7a08f0e69e91e79fbf7729f718 |
publicationDate |
2017-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2017210214-A1 |
titleOfInvention |
Methods of drug therapy selection for breast cancer patients based on her2 and her3 pathway subtyping |
abstract |
Provided herein is a method for determining whether a human subject with breast cancer will respond to a therapy comprising a tyrosine kinase inhibitor or a biologic. The method includes determining the expression level and/or activation level of various signal transduction molecules such as truncated HER2 protein, full-length HER2 protein, HER3 protein, PI3K protein, and others. The determination of likely response to a tyrosine kinase inhibitor therapy or a biologic therapy involves comparing the expression level and/or activation level of the signal transduction molecule(s) to a reference expression/activation level for the specific signal transduction molecule(s). |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109734799-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020205632-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020059789-A1 |
priorityDate |
2016-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |