Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_78587acbfc8d4c9e9ac3baa7021087d7 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0331 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2207-12 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0271 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 |
filingDate |
2016-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6fbca913982893eda8a461b22d6a26e6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c9151964196ce870e6f6fb4ba28a8ff6 |
publicationDate |
2017-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2017079646-A1 |
titleOfInvention |
An efficient, scalable patient-derived xenograft system based on a chick chorioallantoic membrane (cam) in vivo model |
abstract |
Embodiments of the disclosure encompass systems that utilize chick chorioallantoic membranes (CAM) as models for cancer xenografts, including at least patient-derived xenografts (CAM-PDX). In particular embodiments, the system employs the CAM-PDX to graft and culture different types of tumor tissue on a single or multiple eggs. In specific embodiments multiple tumor regions of a single tumor are cultured on a single egg. Frozen tissue is successfully revived, in specific embodiments. Downstream applications following successful establishment of CAM-PDX models are encompassed. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021214137-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109006694-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108990900-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109929797-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020075168-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020089561-A1 |
priorityDate |
2015-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |