abstract |
Provided is an amyloid fiber formation inhibitor comprising a compound represented by general formulas (I)-(III): (in the formulas, Q represents -C(=O)- or the like; X represents -C(=O)-, -NH-C(=O)-, or the like; Y represents -(CH 2 ) m -, or the like; Z represents -(CH 2 ) n -; R 1 , R 2 , and R 3 each independently represent a hydrogen atom, an alkyl group, a hydroxyalkyl group, an alkylaminoalkyl group, or the like; and R 4 represents an amino group, an alkylamino group, or the like), a pharmacologically acceptable salt thereof, or a solvate of these. |