| abstract |
[Problem] The purpose of the invention is to provide a compound that can be utilized as an antiviral agent, in particular as an anti-RNA viral agent, and especially as an anti-RS viral agent. [Solution] The invention provides a compound as indicated by formula (1) (in formula (1), R1 each independently represent a hydrogen, halogen, hydroxyl, amino, carboxyl, C1-C6 alkyl, C1-C6 alkoxyl, C1-C6 halogenoalkyl, C1-C6 alkoxycarbonyl, C1-C6 alkylamino, C2-C5 alkenyl, C3-C6 cycloalkyl, or optionally substituted aryl; R2 each independently represent a hydrogen, C1-C6 alkyl, C1-C6 halogenoalkyl, C2-C5 alkenyl, C3-C6 cycloalkyl, optionally substituted aryl, or heterocyclic group; and one or more R1 may be present in the same ring), an isomer thereof, a pharmaceutically acceptable salt of these, or a mixture of these. The compounds provided by the invention are useful as drugs for the prevention or treatment of infection by virus, especially RS virus, and in particular infection in the lower airways (e.g., bronchiolitis, pneumonia, etc.). |