Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a42432b7432aac5b0a227be23fe13c26 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-118 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2818 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2827 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57492 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39558 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-10 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
filingDate |
2015-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f9c75469864d2d83dda989a24e7f0ce |
publicationDate |
2016-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2016049385-A1 |
titleOfInvention |
Methods and compositions for cancer treatment and treatment selection |
abstract |
In some aspects, the disclosure provides methods of treating cancer or an infection. In some aspects, the disclosure provides methods of enhancing the efficacy of treatment with an immune checkpoint inhibitor. In some embodiments the methods comprise administering a complement inhibitor and an immune checkpoint inhibitor to a subject with cancer or an infection. In some aspects, the disclosure provides methods of identifying a subject who is an appropriate candidate for treatment with an immune checkpoint inhibitor. In some aspects, the disclosure provides methods of identifying a subject who is an appropriate candidate for treatment with an immune checkpoint inhibitor and a complement inhibitor. In some embodiments the methods comprise determining whether the subject is an appropriate candidate for treatment with an immune checkpoint inhibitor and a complement inhibitor based on an assay of a complement system biomarker in the subject or in a sample obtained from the subject. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20210105270-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102401657-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10007766-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019238056-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018071668-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9920123-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10950348-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2017039345-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017180815-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110831544-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2755903-C2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023085690-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018187813-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102395580-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11150238-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11040107-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021167177-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11278592-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11710539-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019074842-A1 |
priorityDate |
2014-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |