| abstract |
The present invention relates to a microvesic!e comprising: (i) a membrane- associated protein comprising at least one first dimerization domain, (ii) a carrier protein comprising at least one second dimerization domain, and (iii) a solute that binds to the carrier protein, wherein the solute is selected from the group of: DNA, RNA, protein, carbohydrate, ribosomes, mitochondria, and small molecules. Also provided are ceils, reagents and kits that find use in making the microvesicles, as well as methods of using the microvesicies, e.g., in research and therapeutic applications. |