http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015133147-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e5e7a9f9b6aa26ac3a15dfb7b4c82bc2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_65705dca71d48b681c3aeb098ccd6291 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0331 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-105 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0696 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0271 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0735 |
| filingDate | 2015-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c0496589032d3e2623c1591170490d3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94abd3a00cadfc58adf9ed3bd8d3ea63 |
| publicationDate | 2015-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2015133147-A1 |
| titleOfInvention | Diseased humanized model animal and teratoma tissue |
| abstract | Provided is a diseased humanized model animal that makes it possible to perform in vivo examination of human tissue and human cells that are in a diseased state. Human pluripotent stem cells are transplanted into the tissue of an immunodeficient animal, a teratoma is formed, and a disease is induced by intraperitoneally administering a disease-inducing substance. The disease-inducing substance is streptozotocin or alloxan. The accumulation of neutral fat was observed in the heart muscle and vascular smooth muscle within a teratoma that grew from a mouse that was subjected to a transplant of iPS cells derived from a healthy human and that developed diabetes after streptozotocin was administered thereto two months later. |
| priorityDate | 2014-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 192.