| abstract |
The present invention provides a VEGF-BPB specifically binding to a VEGF, a nucleic acid molecule coding same, a recombinant vector comprising the nucleic acid molecule, and a pharmaceutical composition for preventing or treating angiogenesis-related diseases, comprising the VEGF-BPB. In the VEGF-BPB according to the present invention, two distal VEGF-target binding regions, which are bound to either end of a structure stabilizing region, bind to targets cooperatively and synergetically, thereby inhibiting VEGF-induced angiogenesis. |