http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20120125455-A
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K19-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 |
filingDate | 2010-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2012-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-20120125455-A |
titleOfInvention | Bipodal Peptide Binder for Intracellular Target Binding |
abstract | The present invention provides a method for preparing a stabilizing region comprising: (a) a structure stabilizing region comprising parallel, antiparallel or parallel and antiparallel amino acid strands formed with interstrand noncovalent bonds; (b) a target binding region I and a target binding region II bound to both ends of the structural stabilization site and comprising randomly selected n and m amino acids, respectively; And (c) intracellular targeting bipodal peptide binders that specifically bind to intracellular target molecules, including cell membrane-penetrating peptides (CPPs) bound to the structural stabilization site or the target binding site, and to their preparation. The method relates to intracellular target molecules of the present invention, which can be used for medicament, in vivo molecular imaging, in vitro cell imaging and drug delivery targeting, and is also useful as an escort molecule. Can be. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20190001859-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015099302-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9617344-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101531944-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015156644-A1 |
priorityDate | 2009-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1389.