Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_39a818160b74bc65846008eb57d5b12a |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3633 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3687 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3695 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L15-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-36 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-36 |
filingDate |
2014-09-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_661203ea08a21366e7288c22967f53cf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f512ceee6a7b39327ac5fe7c0a487e98 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_022b3adb51a8eb10b967ef0743cd95f3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d28d212363f86ec29c02f64290c854a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8890c4e3c949c6a49a88d1449791bbd |
publicationDate |
2015-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2015035115-A1 |
titleOfInvention |
Method for enzymatic treatment of tissue products |
abstract |
Methods for treating tissue matrices and tissue matrices produced according to the methods are provided. The methods can include treating a tissue matrix with a proteolytic enzyme to produce a desired pliability of the tissue matrix and/or to control the immunogenicity of the tissue matrix. The methods can also comprise performing an assay to determine if contacting the at least one collagen-containing tissue matrix with a proteolytic enzyme has altered the at least one collagen- containing tissue matrix to reduce a human immune response to the tissue matrix. The methods can comprise treatment with alcalase under conditions controlled to produce a desired pliability without unacceptable alteration in collagen structure. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10792394-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11052175-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017210109-A1 |
priorityDate |
2013-09-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |