Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e6c6f4df9d92b667762a8445c73d4892 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-112 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-118 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-56 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5748 |
filingDate |
2014-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3710dd367b4ae93e2ec049372bf51fd6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_41f63523c2282795a60d9d416cfe0e2d |
publicationDate |
2014-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2014184679-A2 |
titleOfInvention |
Method for the prognosis and treatment of renal cell carcinoma metastasis |
abstract |
The present invention relates to a method for the prognosis of bone metastasis in renal cell carcinoma which comprises determining if the c-MAF gene is amplified in a primary tumor sample. Likewise, the invention also relates to a method for determining the tendency to develop bone metastasis with respect to metastasis in other organs, which comprise determining the c- MAF gene expression level, amplification or translocation. The invention also relates to a method for predicting early bone metastasis in a subject suffering renal cell carcinoma. The invention also relates to a c-MAF inhibitor as therapeutic agent for use in the treatment of renal cell carcinoma metastasis. The invention relates to kits for predicting bone metastasis and predicting the clinical outcome of a subject suffering from bone metastasis. Finally, the invention relates to a method for typing of a subject suffering renal cell carcinoma and for classifying a subject from renal cell carcinoma into a cohort. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11352673-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10793642-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11041861-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11596642-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9702878-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11041213-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11591599-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10114022-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10119171-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11654153-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109790582-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10866241-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109790582-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11072831-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10006091-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10047398-B2 |
priorityDate |
2013-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |