| abstract |
This α,α-difluoroacetaldehyde production method involves reacting α,α-difluoroacetic acid esters with hydrogen gas (H 2 ) in the presence of a ruthenium catalyst. By adopting specific reaction conditions (in particular, a reaction medium and reaction temperature), it is possible to selectively obtain α,α-difluoroacetaldehyde, which is a partial reductant of hydrogenation, and this can be an alternative method to hydride reduction, which is difficult to implement industrially. |