abstract |
The present invention is directed to Benzomorphan Analog compounds of the Formula I", Formula IA", Formula IB", Formula IC", or Formula ID" as shown below; and related Formula I', Formula IA', Formula IB', Formula IC', or Formula ID'; Formula I, Formula IA, Formula IB, Formula IC, or Formula ID;wherein R 1 , R 2a , R 2b , R 3 and R 4 are as defined herein Compounds of the Invention are useful for treating pain, constipation, and other conditions modulated by activity of opioid and ORL-1 receptors. |