Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0ab260871da632c5eb5d6d5af5c11b12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b6171684de68ce62ef3fbf1655618249 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fa22228509df40cb29939c3c37d1f736 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e5351c62aee4203f2be2944f21a6def2 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-23 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-231 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-34 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-121 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-46 |
filingDate |
2012-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e64e26614561bad62f36ae39a58b891 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_95c0c436e08beae580ef2aea021c893d |
publicationDate |
2014-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2014042292-A1 |
titleOfInvention |
Composition comprising protein kinase c activator for promoting stem cell adhesion, and method for promoting stem cell adhesion |
abstract |
The present invention relates to a composition comprising a protein kinase C activator for promoting stem cell adhesion and to a method for promoting a stem cell adhesion. The protein kinase C activator according to the present invention promotes the phosphorylation of focal adhesion kinase (FAK) which is a signal transduction molecule associated with cell adhesion capacity in stem cells, and increases the expression of paxillin, talin, vinculin and Rac1 which is a GTPase, and thus enables stem cells to effectively adhere to a damaged area of the myocardium. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023282424-A1 |
priorityDate |
2012-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |