| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a251ae79dd7a008d95010b238c6aa1f8 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-65
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0662
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-07
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-071
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
| filingDate |
2007-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad7e20bc35e5d70da825ee4a5c5b790a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6c36cad33329205c7fe2687e33b8bbea
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_992c79216ba173cf95bf3c06842e98ee |
| publicationDate |
2009-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20090025989-A |
| titleOfInvention |
Mesenchymal stem cell with improved tissue regeneration ability and method for producing same |
| abstract |
The present invention relates to mesenchymal stem cells with improved tissue regeneration ability, and more particularly, to mesenchymal stem cells treated with antisense RNA of lzts2 gene and suppressed the expression of lzts 2 gene, and a method for producing the same.n n n According to the present invention, the cell proliferation was improved by inhibiting the expression of lzts2 gene in human mesenchymal stem cells, and it was also found that the mesenchymal stem cells suppressed by lzts2 gene expression in the ischemic animal model transplantation experiments promote damaged tissue cell regeneration. . Therefore, based on the mechanism regulating the expression of the lzts2 gene of the mesenchymal stem cells can be used for the development of mesenchymal stem cell therapeutics useful for promoting damaged tissue regeneration. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014042292-A1 |
| priorityDate |
2007-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |