Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_618b3747eb5c7a8510b9a893c934685d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eab56e4fe8837840887f41af83e328ee |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-552 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-522 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12R2001-42 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-205 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0275 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-42 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-02 |
filingDate |
2013-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_65dd4357986af7606154b6a4ab39bd82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5fed956b969fd6f0abb693e632e9829d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a7c94bc83283f15271ec92766e00c66f |
publicationDate |
2014-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2014037103-A1 |
titleOfInvention |
Live attenuated metabolic drift vaccine against fowl typhoid |
abstract |
The present invention relates to the development of a new live fowl typhoid (FT) vaccine candidate against Salmonella Gallinarum (SG), with two independent attenuating mutations based on metabolic drift (MD), spontaneous chromosomal mutations. Such vaccine candidate fulfills the security demand of the World Health Organization (WHO). The vaccine proved to be genetically stable, safe and effective in experimental studies. This attenuated vaccine strain is designed sufficiently invasive to induce immunity in poultry, in particular chickens, and the vaccinated animals were protected against experimental SG challenge. The vaccine can be used for chicken and can be administered orally which is an easy and cost effective alternative to injection. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102077701-B1 |
priorityDate |
2012-09-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |