| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_689d532e7f712c780cb4cec200f16fef
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_38dcf790bac4c5ac5f10d6177997b205 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-522
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0275 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-112 |
| filingDate |
2005-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c2ec61bd138120825ea052f40962da9d |
| publicationDate |
2005-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2005078068-A1 |
| titleOfInvention |
Live attenuated salmonella for use as vaccine |
| abstract |
The present invention relates to live attenuated Salmonella cultures for use as vaccines. The Salmonella cultures of the present invention have a substantially reduced capacity to grow and replicate in the presence of bile. The reduced capacity for growth is due to a metabolic-drift mutation induced by exposure to a combination of nalidixic acid and rifampicin for a time and under conditions sufficient to induce the mutation. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014037445-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014037103-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3415643-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10828362-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2015536142-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3714899-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EA-030355-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022007326-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104995292-A |
| priorityDate |
2004-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |