| abstract |
Provided is a 4,6-hexadecadiene-2,4-dicarboxylic acid derivative or pharmaceutically acceptable salt thereof or the like, having anti-tumour activity and represented by general formula (I): [in the formula, R 1 represents a hydroxy, –OR 3 (in the formula, R 3 represents a lower alkyl that may have a substituent, or an aliphatic heterocyclic group that may have a substituent) or –NR 4 R 5 (in the formula, R 4 and R 5 are the same or different, and each represent a hydrogen atom, or a lower alkyl that may have a substituent), and R 2 represents a hydroxy or –OR 6 (in the formula, R 6 represents a lower alkyl that may have a substituent or an aralkyl that may have a substituent)]. |