| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1b0c198757da18cf77dfbdcef00abb70 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2602-24 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C271-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-582
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y601-01026
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-006
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-13
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-93 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-00 |
| filingDate |
2013-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d29113d342a574d267cca984bf968ae
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5036a7cc1af5541532cbf22eb6175f66 |
| publicationDate |
2013-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2013171485-A1 |
| titleOfInvention |
Methods of incorporating an amino acid comprising a bcn group into a polypeptide using an orthogonal codon encoding it and an orthorgonal pylrs synthase. |
| abstract |
The invention relates to a polypeptide comprising an amino acid having a bicyclo[6.1.0]non-4-yn-9-ylmethanol (BCN) group, particularly when said BCN group is present as: a residue of a lysine amino acid. The invention also relates to a method of producing a polypeptide comprising a BCN group, said method comprising genetically incorporating an amino acid comprising a BCN group into a polypeptide. The invention also relates to an amino acid comprising bicyclo[6.1.0]non-4-yn-9-ylmethanol (BCN), particularly and amino acid which is bicyclo[6.1.0]non-4-yn-9-ylmethanol (BCN) lysine. In addition the invention relates to a PylRS tRNA synthetase comprising the mutations Y271M, L274G and C313A. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017030156-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10774039-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2019127488-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2017030156-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10906990-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11642415-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11732001-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018175788-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111849929-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11560384-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106010507-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10751417-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11787877-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11389541-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021001814-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3971169-A1 |
| priorityDate |
2012-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |