| abstract |
The present invention provides a composition for preventing hair loss or promoting hair growth containing octaphlorethol A (OPA) as an active ingredient. The extract of Ishige sinicola extract increases the length of hair fiber and the octaphlorethol A isolated from the Ishige sinicola extract promotes the growth of dermal papilla cells, inhibits 5α-reductase activity, and increases PGE2 production, which contribute to hair growth. Accordingly, the octaphlorethol A can be useful as a raw material for a functional cosmetic composition or pharmaceutical composition for preventing hair loss or promoting hair growth. Additionally, since octaphlorethol A is a natural material and thus edible, the composition of the present invention containing octaphlorethol A as an active ingredient has the advantage of being safe even when used for lengthy periods of time. |