| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5cf2493503a736feb8eda9c3b556b152
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f6a554656e00a2368fce50f2797440f6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d7de427a83362569ceab36bc754674e0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1c89ce4d9ac03f9acd8ddede1162f94d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_714592e495d9a3a6b34afec1597c3198 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-112 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57496
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate |
2013-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f3129243c63336d3ca223d8d89db309
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d849e9e462bb4671907ea8903c3d93c7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_22bbeb59eca15fc1f655e903357ccdd2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fbec6237c619ff0d0eb164d518e5228c |
| publicationDate |
2013-10-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2013148775-A1 |
| titleOfInvention |
Predictive biomarker useful for cancer therapy mediated by a cdk inhibitor |
| abstract |
The present invention provides a predictive biomarker whose expression level is useful for identifying patients responsive to a therapeutically effective dose of a CDK inhibitor. In one embodiment of the invention, the predictive biomarker is the ratio of MCL-1 to BCL-xL (MCL-1:BCL-xL ratio) and the CDK inhibitor is SCH 927965 (Dinaciclib). |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016113187-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019232467-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107206092-A |
| priorityDate |
2012-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |