| abstract |
Provided is a compound which has an outstanding GPR119 agonist action. Specifically, a compound represented by general formula (I) or a pharmaceutically permitted salt thereof is provided. (I) [In formula (I), substituent group A represents phenyl or a 5 or 6-membered heteroaryl, W represents a single bond, -O-, -NH-, -OCH 2 - or -CH 2 O-, X represents a nitrogen atom or CR 21 , Y 1 represents a nitrogen atom or CR 22 , Y 2 represents a nitrogen atom or CR 23 , Y 3 represents a nitrogen atom or CR 24 , R 21 , R 22 , R 23 and R 24 which can be the same or different represent a hydrogen atom or C 1-6 alkyl, and substituent group B represents (a) C 2-6 alkyl, C 3-8 cycloalkyl, (C 3-8 cycloalkyl)C 1-6 alkyl, (aryl)C 1-6 alkyl or (saturated heterocyclyl)C 1-6 alkyl, (b) -COOR 31 (R 31 represents C 1-6 alkyl, C 3-8 cycloalkyl, aryl or saturated heterocyclyl), or (c) 5 or 6-membered heteroaryl represented by general formula (β). However, a structure represented by formula (A) is excluded.] |