| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dea1b4e785af26a6c53c2cf6b40fd432
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b6656ff46abe2681b8301b139c0faf99
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5ad4128a8875759ff06a2aabac940faa |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D475-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D475-08 |
| filingDate |
2010-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_11cb4f8d63201d371f6be7d1003bc583
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c4b50a746013fed4db431ff0a622621 |
| publicationDate |
2012-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2012074496-A1 |
| titleOfInvention |
A new method for producing antifolate agents having glutamic acid part in their structure |
| abstract |
A new method for producing antifolate agents having glutamic acid part in their structure is developed by protecting carboxyl groups of glutamic acid or its N-subsituted derivatives as cyanomethyl ester to give compounds of formula (II) which are hydrolyzed under very mild conditions to afford antifolate agents in high yield with high analytical and optical purity. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103588775-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103588775-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104447724-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112851676-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10513665-B2 |
| priorityDate |
2010-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |