http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103588775-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D475-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D475-04 |
| filingDate | 2013-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103588775-B |
| titleOfInvention | Pralatrexate degradation impurity and preparation method thereof |
| abstract | The present invention relates to Pralatrexate degradation impurity and preparation method thereof.Specifically, this Pralatrexate degradation impurity is N [4 [1 [(2 amino 4 hydroxyl 6 pteridyl) methyl] 3 butine 1 bases] benzoyl] the L glutamic acid shown in following formula (I).Its synthesis obtains target compound by being substituted by 4 [1 [(2,4 diaminourea 6 pteridyl) methyl] 3 butine 1 bases] benzoic acid compounds, be condensed, hydrolyzing.The method first passage chemosynthesis obtains formula (I) compound, and can be separated efficiently and rapidly and obtain target compound. |
| priorityDate | 2013-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 50.