http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012028709-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ef9f570a6c931165dd441ad7c89df2c1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a2a54b1b228796105464f134654a470e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f3acf8670babc0ba801847640e53121c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bb950ff54569b4bc9f4308c1b4a3555b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7a913ba44530aa6ef1dd1736141b0cae |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0042 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y106-02004 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-02 |
| filingDate | 2011-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_296b8ff4ccac0b51800cf24dd96c87e8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_34f643b76a203f3debf0b771ac21175a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_18836be3db028f889ba5a604671fef4e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_061619d142b439ab7048e9d4da9e1c4f |
| publicationDate | 2012-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2012028709-A2 |
| titleOfInvention | Novel monooxygenase variants |
| abstract | The present invention relates to a nucleic acid molecule encoding a polypeptide having cytochrome P450 monooxygenase activity, wherein said polypeptide comprises a reductase domain that deviates by at least one mutation from (a) the reductase domain of cytochrome P450 BM3, wherein the reductase domain of cytochrome P450 BM3 is represented by SEQ ID NO: 1; or (b) a reductase domain having at least 95% sequence identity to SEQ ID NO:1; and wherein said mutation(s) result(s) in an increased cytochrome P450 monooxygenase activity as compared to a polypeptide comprising the reductase domain of SEQ ID NO: 1. The present invention also relates to a vector comprising the nucleic acid molecule of the invention and a host transformed with the vector. Furthermore, the invention relates to a method of producing a polypeptide comprising culturing the host of the invention as well as to a polypeptide encoded by the nucleic acid molecule of the invention or produced by the method of the invention. The present invention further relates to the use of the polypeptide of the invention in biotransformation or fine chemical synthesis, to an oligo- or polynucleotide which specifically hybridizes to the nucleic acid molecule of the invention as well as to a composition and to a kit. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014195507-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112961844-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112961844-A |
| priorityDate | 2010-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 149.