Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_23ff530b8e69ccb42409d8056861276f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_396468ddec84563d7c858c57423f38af http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cee60a56f9a34647145273ea9fb98119 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fd495388214645d9f73a84588b77ebd0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8ab9630f1a275ab9aa62687fc1be2deb http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1c5b5cfbdfd88649fd8a86c05aa082f1 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00862 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00889 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-0086 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00833 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B59-008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J19-0093 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-1077 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B59-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-13 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F5-00 |
filingDate |
2011-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ae6129d7aa618cd3734e32d16e4073a5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3b73a93b76fa92d13fc666821e337c82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ecfdde6ca8318dc8138b90a9f6dada34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8aa7c7cea3a429cf7bc245fedfa3bd0a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8553e549cf3162ccde57652a4aebe185 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0243c0b5858666e70c921bb010a74c49 |
publicationDate |
2012-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2012027527-A2 |
titleOfInvention |
Microreactor and method for preparing a radiolabeled complex or a biomolecule conjugate |
abstract |
A microreactor for preparing a radiolabeled complex or a biomolecule conjugate comprises a microchannel for fluid flow, where the microchannel comprises a mixing portion comprising one or more passive mixing elements, and a reservoir for incubating a mixed fluid. The reservoir is in fluid communication with the microchannel and is disposed downstream of the mixing portion. A method of preparing a radiolabeled complex includes flowing a radiometal solution comprising a metallic radionuclide through a downstream mixing portion of a microchannel, where the downstream mixing portion includes one or more passive mixing elements, and flowing a ligand solution comprising a bifunctional chelator through the downstream mixing portion. The ligand solution and the radiometal solution are passively mixed while in the downstream mixing portion to initiate a chelation reaction between the metallic radionuclide and the bifunctional chelator. The chelation reaction is completed to form a radiolabeled complex. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019036399-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-5857075-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014102944-A1 |
priorityDate |
2010-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |