| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_31e8f75c4bfe7b7ffd6c89849b9c9e8e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c9c9f934949e24a085244e630f506098
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7bc6eab1a5d97cea56ec9c2bbf9e69da |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-603
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-604
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-602
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-606
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2506-1307 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6881
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0696
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56966 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-00 |
| filingDate |
2011-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c2920e88bfb4565a84040cc5d434019c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_10a26c3b442d2027d1f62a1ccf0ccd78 |
| publicationDate |
2011-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2011159692-A1 |
| titleOfInvention |
Improved methods for producing induced pluripotent stem cells |
| abstract |
The invention provides improved methods for producing induced pluripotent stem cells (iPSC) from adult fibroblasts. The methods include contacting adult fibroblasts with a reprogramming composition suitable for reprogramming the adult fibroblasts to iPSC, under conditions effective for the reprogramming composition to penetrate the adult fibroblasts, followed by culturing the contacted fibroblasts for a time period sufficient for the cells to be reprogrammed. The cultured cells are then sorted to select cells based upon their expression of the cell membrane surface markers CD13 NEG SSEA4 POS Tra-1-60 POS . iPSC colonies are then identified from the sorted cells. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9783786-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11268069-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017066634-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014170549-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11441126-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014000814-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10844356-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102965393-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102965393-A |
| priorityDate |
2010-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |