abstract |
The invention relates to a method for inducing pluripotent stem cells, wherein a mammalian cell is contacted with a compound characterized by a general formula 1 wherein R 1 is (CH 2 ) m E, with E being CCH or CN and m being 0, 1, or 2, and R 2 is selected from F, CI, Br, OR 3 and R 3 , with R 3 being selected from H, (CH y F 2-y ) n CH X F 3-X , with n=0 or 1. The invention further relates to stem cells obtained by the method of the invention, and culture media comprising the compound of the invention. |