Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_011e59e717d3bc01952e7705101414e9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_45c0162af738c3bb7a0605ecd39240b3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1763f7f78d01cad638210d060676591a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_001e2f9f3c92a9c2206e3dfbcb9a99c3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_17229efb3b81b88b0a4409794a58c9aa http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3cb58d2913265236542e471b8167ce69 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2035-124 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2533-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-12 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0663 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0622 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0062 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3675 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-00 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-12 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0775 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-071 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-04 |
filingDate |
2011-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0422642d40b69fa73c98ea61824b8a23 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5752f500c0607a64847fa4c5942ca8c6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0cae99f9bbdd785fb9e00bd19f0a9861 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c7b4959886cc8cfc73c4d640f594c0bb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_88d0913dd3f85dbf9e3e2bc1309b41ea |
publicationDate |
2011-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2011097330-A2 |
titleOfInvention |
Engineered biological nerve graft fabrication and application thereof |
abstract |
An engineered three-dimensional structure includes living cells cohered with each other. The living cells suitably include Schwann cells and at least one other type of cell. The cells accompanying the Schwann cells can suitably be bone marrow stem cells or another type of cell having one or more anti-inflammatory properties. The structure is suitably a graft that facilitates restorative axon growth when the graft is implanted between the proximal and distal stubs of a severed nerve in a living organism. The graft can optionally include a plurality of acellular conduits extending between opposite axial ends of the graft. Bio-printing techniques can be used to assemble a three-dimensional construct that becomes through maturation an axon-guiding graft, by stacking a plurality of multicellular bodies, each of which includes a plurality of living cells cohered to one another to sufficiently to avoid collapsing when the multicellular bodies are stacked to form the structure. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11577450-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10094821-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11577451-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9227339-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11413805-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11789011-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9855369-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10967560-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9752116-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9442105-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10782217-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9315043-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11254901-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11518978-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11124774-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9481868-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11529436-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11530380-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10808218-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11299705-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10174276-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108187148-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11543336-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2018171065-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016514968-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10400219-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2756073-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10962526-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2014531204-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9983195-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9222932-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9556415-B2 |
priorityDate |
2010-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |