http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011068206-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_372d8ded45e78d8ca6a76149a7bcf0ae http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2c8ae0e542d979d84e5ed065ae81772c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_04379a0c835de10591375530f7123531 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_696ca0ae93d5cf5a686273601361781f |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P13-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P41-006 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P41-00 |
filingDate | 2010-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_307ef90aac9fed54c5b7ca0ba234de4d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1f3c6c50e0df7f07009e8dabcbccd730 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b5be1b505d2f9eb9ccf1aa67fc06fe6 |
publicationDate | 2011-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2011068206-A1 |
titleOfInvention | Process for production of optically active amino acid or optically active amino acid amide |
abstract | Disclosed is a process for producing D- or L-tert-leucine or D- or L-tert-leucineamide by reacting DL-tert-leucineamide with a biological catalyst selected from the group consisting of an enzyme capable of hydrolyzing DL-tert-leucineamide stereoselectively, cells of a microorganism having the enzyme, a material produced by any treatment of the cells, an immobilized enzyme produced by immobilizing the enzyme onto a carrier, immobilized cells produced by immobilizing the cells onto a carrier, and an immobilized cell treatment product produced by immobilizing the cell treatment product onto a carrier to thereby hydrolyze DL-tert-leucineamide. The process is characterized in that the hydrolysis is carried out while separating ammonia that is produced by the hydrolysis from a hydrolysis reaction solution. In the process, the activity per unit amount of the enzyme, the cells or the cell treatment product and per unit time period is kept at a high level in the enzymatic reaction for hydrolyzing an amino acid amide stereoselectively. Therefore, the concentration of a raw material amino acid amide in a reaction solution can be increased without the need of increasing the amount of the cells or a pH-adjusting acid, and consequently the productivity of optically active tert-leucine or optically active tert-leucineamide can be improved to a great extent without increasing the production amount of a waste salt or waste cells. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2014167047-A |
priorityDate | 2009-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 39.