Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ee6aa623af81d87a981aab4ca3c30aef http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f2d7feb61f54d5912db1c4f3d298c4fd http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d094dcaf29a68481dc3e95494280c334 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_05c1b2a30dd695a6bdf245e82602e476 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f8903a516e8bc59fe6f2f31812f04032 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0006 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C29-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-18 |
filingDate |
2010-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_677aa3d70412ed447dff74cd9b2fc078 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_89623eb020abe3f603926640fc34f898 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_de70eb397dceb325b95c22e78500e27b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_551e16e54270a4cd13fa6bc7482bde59 |
publicationDate |
2011-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2011012702-A1 |
titleOfInvention |
Mutant glycerol dehydrogenase (glydh) for the production of a biochemical by fermentation |
abstract |
The present invention concerns a method for the production of 1,2-propanediol, comprising culturing a micro organism modified for an improved production of 1,2- propanediol in an appropriate culture medium and recovery of the 1,2-propanediol which may be further purified wherein the microorganism expresses a glycerol dehydrogenase (GlyDH) enzyme the inhibition of which activity by NAD+ and/or its substrate and/or its product is reduced. The present invention also relates to a mutant glycerol dehydrogenase(Gly DH) comprising at least one amino acid residue in the protein sequence of the parent enzyme replaced by a different amino acid residue at the same position wherein - the mutant enzyme has retained more than 50% of the glycerol dehydrogenase activity of the parent enzyme and - the glycerol dehydrogenase activity of the mutant GlyDH is less inhibited by NAD+ and/or by its substrate as compared to the parent enzyme and/or by its product as compared to the parent enzyme. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012172050-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10889840-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017042602-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018122388-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3342873-A1 |
priorityDate |
2009-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |