http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010134096-A2

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filingDate 2010-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2010-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2010134096-A2
titleOfInvention Yeast strain expressing modified human cytochrome p450 reductase and/or cytochrome p450 gene
abstract The present invention provides modified polynucleotide sequences coding for human cytochrome P450 reductase, human cytochrome P450 and human cytochrome b5. Further a genetically modified protease deficient yeast strain comprising integrated modified human cytochrome P450 reductase gene is provided in the present invention. The present invention also provides a genetically modified protease deficient yeast strain comprising integrated modified human cytochrome P450 reductase gene and a plasmid comprising modified polynucleotide sequence coding for cytochrome P450s and/or modified polynucleotide sequence coding for cytochrome b5. The yeast strain(s) disclosed in the present invention have been shown to express catalytically active cytochrome P450s with higher specific activity
priorityDate 2009-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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