| abstract |
PCT No. PCT/FR92/00682 Sec. 371 Date Jan. 13, 1994 Sec. 102(e) Date Jan. 13, 1994 PCT Filed Jul. 15, 1992 PCT Pub. No. WO93/02200 PCT Pub. Date Feb. 4, 1993Yeast strains and a method of expression in yeast of the monooxygenase activity of heterologous cytochromes P450 are disclosed. Within the genome of the yeast strain, genes for NADPH-cytochrome P450 reductase and cytochrome b5 are stably integrated and coexpressed. The genome is transformed with a plasmid carrying a cassette for the expression of a heterologous P450 gene. |