| abstract |
Disclosed are: a pharmaceutical composition which comprises a monoclonal antibody having an excellent affinity and an excellent neutralizing ability for human cytomegalovirus (HCMV) (which a virus causing various disease conditions) and also having an inhibitory ability on the intercellular infection of HCMV and an antigen-binding fragment of the monoclonal antibody; a monoclonal antibody which can bind specifically to a specific sequence occurring in an AD2 region of gB glycoprotein of HCMV, has an excellent affinity and an excellent neutralizing ability for HCMV, and also has an inhibitory ability on the intercellular infection of HCMV, and an antigen-binding fragment of the monoclonal antibody; a pharmaceutical composition comprising the antibody or a fragment thereof; and others. |