| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b7317808024e524eea40a6c5a5ad6a22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_274c8be79fb7465b1b485b5846691a39
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cac63eef4450f2123f965a9aab115224
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cf3fb1168ef85de4ee716db3db3d3ccb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_65bdcdeddd83ed782bc33845e62acc9e |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N5-1038 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N5-103
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16H50-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16H70-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16H20-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16H10-40 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16H20-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16H50-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16H10-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16H70-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61N5-10 |
| filingDate |
2010-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f5289680e76f995086aeaae859e556e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b3f3c5dc0ac6296c7414715e319dff57
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_38c283f2f3cbeb0e11e3bc6b11d5948d |
| publicationDate |
2010-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2010109357-A1 |
| titleOfInvention |
Marker adapted normal tissue complication probability |
| abstract |
A therapy system includes a diagnostic image scanner (12) that acquires a diagnostic image of a target region to be treated. A planning processor (70) is configured to generate a patient specific adaptive radiation therapy plan based on patient specific biomarkers before and during therapy. A first set of patient specific biomarkers is determined then used for the determination of a first normal tissue complication probability (NTCP) model and a first tumor control probability (TCP) model. A radiation therapy device (40) administers a first dose of radiation to the target region with a protocol based on the first NTCP model and the first TCP model. A second set of patient specific biomarkers is determined. A relationship between the first set and second set of patient specific biomarkers is used to determine a second NTCP model and a second TCP model. The radiation therapy device (40) administers a second dose of radiation to the target region with a protocol based on the second NTCP model and second TCP model. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-102011082181-B3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103648585-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013001507-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10828507-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103648585-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015121597-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102542153-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015121596-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2016008629-A1 |
| priorityDate |
2009-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |