| abstract |
Provided is a compound useful in medicinal compositions, for example, remedies for diseases in which 17βHSD type 5 participates.nAs the results of intensive studies on compounds possibly useful as remedies for diseases in which 17βHSD type 5 participates, it is found out that an indole compound having a substituted carbamoyl group at the 2-position has a potent 17βHSD type 5 inhibitory activity and is likely usable as a remedy and/or a preventive for diseases in which 17βHSD type 5 participates, for example, benign prostatic hyperplasia and prostate cancer without showing any side effect caused by a decrease in testosterone level. |